Decreased Efficacy of Doxorubicin Corresponds With Modifications in Lipid Metabolism Markers and Fatty Acid Profiles in Breast Tumors From Obese vs. Lean Mice

Breast cancer cells modulate lipid and fatty acid metabolism to sustain proliferation. The role of adipocytes in cancer treatment efficacy remains, however, to be fully elucidated. We investigated whether diet-induced obesity (DIO) affects the efficacy of doxorubicin treatment in a breast tumor-bear...

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Detalles Bibliográficos
Autores principales: Mentoor, Ilze, Nell, Theo, Emjedi, Zaakiyah, van Jaarsveld, Paul J., de Jager, Louis, Engelbrecht, Anna-Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089940/
https://www.ncbi.nlm.nih.gov/pubmed/32257945
http://dx.doi.org/10.3389/fonc.2020.00306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089940/
https://www.ncbi.nlm.nih.gov/pubmed/32257945
http://dx.doi.org/10.3389/fonc.2020.00306

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