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8q24 genetic variation and comprehensive haplotypes altering familial risk of prostate cancer

The 8q24 genomic locus is tied to the origin of numerous cancers. We investigate its contribution to hereditary prostate cancer (HPC) in independent study populations of the Nashville Familial Prostate Cancer Study and International Consortium for Prostate Cancer Genetics (combined: 2,836 HPC cases,...

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Detalles Bibliográficos
Autores principales: Dupont, William D., Breyer, Joan P., Plummer, W. Dale, Chang, Sam S., Cookson, Michael S., Smith, Joseph A., Blue, Elizabeth E., Bamshad, Michael J., Smith, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089954/
https://www.ncbi.nlm.nih.gov/pubmed/32251286
http://dx.doi.org/10.1038/s41467-020-15122-1