Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells

Pluripotency maintenance requires transcription factors (TFs) that induce genes necessary to preserve the undifferentiated state and repress others involved in differentiation. Recent observations support that the heterogeneous distribution of TFs in the nucleus impacts on gene expression. Thus, it...

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Detalles Bibliográficos
Autores principales: Verneri, Paula, Vazquez Echegaray, Camila, Oses, Camila, Stortz, Martin, Guberman, Alejandra, Levi, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089971/
https://www.ncbi.nlm.nih.gov/pubmed/32251342
http://dx.doi.org/10.1038/s41598-020-62235-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089971/
https://www.ncbi.nlm.nih.gov/pubmed/32251342
http://dx.doi.org/10.1038/s41598-020-62235-0

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