Enantioselective three-component aminomethylation of α-diazo ketones with alcohols and 1,3,5-triazines

Enantioselective α-aminomethylation of carbonyl compounds constitutes a powerful protocol for introducing aminomethyl groups to simple organic molecules. However, current strategies rely on nucleophile-based enantioselective activation with inherently activated substrates only, and enantioselective...

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Detalles Bibliográficos
Autores principales: Che, Jiuwei, Niu, Li, Jia, Shikun, Xing, Dong, Hu, Wenhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089982/
https://www.ncbi.nlm.nih.gov/pubmed/32251288
http://dx.doi.org/10.1038/s41467-020-15345-2