Cargando…

Tau protein- induced sequestration of the eukaryotic ribosome: Implications in neurodegenerative disease

The human tau is a microtubule-associated intrinsically unstructured protein that forms intraneuronal cytotoxic deposits in neurodegenerative diseases, like tauopathies. Recent studies indicate that in Alzheimer’s disease, ribosomal dysfunction might be a crucial event in the disease pathology. Our...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Senjuti, Ferdosh, Sehnaz, Ghosh, Amar Nath, Barat, Chandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090008/
https://www.ncbi.nlm.nih.gov/pubmed/32251304
http://dx.doi.org/10.1038/s41598-020-61777-7