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Tau protein- induced sequestration of the eukaryotic ribosome: Implications in neurodegenerative disease
The human tau is a microtubule-associated intrinsically unstructured protein that forms intraneuronal cytotoxic deposits in neurodegenerative diseases, like tauopathies. Recent studies indicate that in Alzheimer’s disease, ribosomal dysfunction might be a crucial event in the disease pathology. Our...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090008/ https://www.ncbi.nlm.nih.gov/pubmed/32251304 http://dx.doi.org/10.1038/s41598-020-61777-7 |