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Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans

Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, we study the roles played by fungal kinases and transcription factors (TFs) in blood-brain barrier (BBB) crossing and brain infection in mice. We use a brain infectivity assay to screen signature-tagged mutagenesis (STM)-based li...

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Detalles Bibliográficos
Autores principales: Lee, Kyung-Tae, Hong, Joohyeon, Lee, Dong-Gi, Lee, Minjae, Cha, Suyeon, Lim, Yu-Gyeong, Jung, Kwang-Woo, Hwangbo, Areum, Lee, Yelin, Yu, Shang-Jie, Chen, Ying-Lien, Lee, Jong-Seung, Cheong, Eunji, Bahn, Yong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090016/
https://www.ncbi.nlm.nih.gov/pubmed/32251295
http://dx.doi.org/10.1038/s41467-020-15329-2