Cargando…
Context is everything: extrinsic signalling and gain-of-function p53 mutants
The TP53 genomic locus is a target of mutational events in at least half of cancers. Despite several decades of study, a full consensus on the relevance of the acquisition of p53 gain-of-function missense mutants has not been reached. Depending on cancer type, type of mutations and other unidentifie...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090043/ https://www.ncbi.nlm.nih.gov/pubmed/32218993 http://dx.doi.org/10.1038/s41420-020-0251-x |