MicroRNA-30a targets BECLIN-1 to inactivate autophagy and sensitizes gastrointestinal stromal tumor cells to imatinib

Gastrointestinal stromal tumors (GISTs), the most widespread type of sarcoma, contain driver gene mutations predominantly of receptor tyrosine kinase and platelet-derived growth factor receptor alpha. However, the inevitable development of resistance to imatinib (IM) cannot be fully attributed to se...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Li, Zhouqi, Liu, Hao, Jiang, Sujing, Wang, Guannan, Sun, Lifeng, Li, Jun, Wang, Xiaochen, Yu, Shaojun, Huang, Jianjin, Dong, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090062/
https://www.ncbi.nlm.nih.gov/pubmed/32251287
http://dx.doi.org/10.1038/s41419-020-2390-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090062/
https://www.ncbi.nlm.nih.gov/pubmed/32251287
http://dx.doi.org/10.1038/s41419-020-2390-7

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