Peroxiredoxin 5 deficiency exacerbates iron overload-induced neuronal death via ER-mediated mitochondrial fission in mouse hippocampus

Iron is an essential element for cellular functions, including those of neuronal cells. However, an imbalance of iron homeostasis, such as iron overload, has been observed in several neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. Iron overload causes neuronal toxi...

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Detalles Bibliográficos
Autores principales: Lee, Dong Gil, Kam, Min Kyoung, Lee, Sang-Rae, Lee, Hong Jun, Lee, Dong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090063/
https://www.ncbi.nlm.nih.gov/pubmed/32205843
http://dx.doi.org/10.1038/s41419-020-2402-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090063/
https://www.ncbi.nlm.nih.gov/pubmed/32205843
http://dx.doi.org/10.1038/s41419-020-2402-7

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