Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma

Earlier diagnosis of pancreatic ductal adenocarcinoma (PDAC) requires better understanding of the mechanisms driving tumorigenesis. In this context, depletion of Epidermal Growth Factor Receptor (EGFR) is known to impair development of PDAC-initiating lesions called acinar-to-ductal metaplasia (ADM)...

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Detalles Bibliográficos
Autores principales: Meyers, Nora, Gérard, Claude, Lemaigre, Frédéric P., Jacquemin, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090067/
https://www.ncbi.nlm.nih.gov/pubmed/32251323
http://dx.doi.org/10.1038/s41598-020-62106-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090067/
https://www.ncbi.nlm.nih.gov/pubmed/32251323
http://dx.doi.org/10.1038/s41598-020-62106-8

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