Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

Aberrant neuroendocrine signaling is frequent yet poorly understood feature of prostate cancers. Membrane metalloendopeptidase (MME) is responsible for the catalytic inactivation of neuropeptide substrates, and is downregulated in nearly 50% of prostate cancers. However its role in prostate carcinog...

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Detalles Bibliográficos
Autores principales: Cheng, Chieh-Yang, Zhou, Zongxiang, Stone, Meredith, Lu, Bao, Flesken-Nikitin, Andrea, Nanus, David M., Nikitin, Alexander Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090072/
https://www.ncbi.nlm.nih.gov/pubmed/32205838
http://dx.doi.org/10.1038/s41389-020-0222-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090072/
https://www.ncbi.nlm.nih.gov/pubmed/32205838
http://dx.doi.org/10.1038/s41389-020-0222-3

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