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Development of encoded Broccoli RNA aptamers for live cell imaging of alphavirus genomic and subgenomic RNAs
Sindbis virus (SINV) can infect neurons and cause encephalomyelitis in mice. Nonstructural proteins are translated from genomic RNA and structural proteins from subgenomic RNA. While visualization of viral proteins in living cells is well developed, imaging of viral RNAs has been challenging. RNA ap...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090087/ https://www.ncbi.nlm.nih.gov/pubmed/32251299 http://dx.doi.org/10.1038/s41598-020-61573-3 |