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Metabolic Engineering of Saccharomyces cerevisiae for Enhanced Dihydroartemisinic Acid Production

Direct bioproduction of DHAA (dihydroartemisinic acid) rather than AA (artemisinic acid), as suggested by previous work would decrease the cost of semi-biosynthesis artemisinin by eliminating the step of initial hydrogenation of AA. The major challenge in microbial production of DHAA is how to effic...

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Detalles Bibliográficos
Autores principales: Zeng, Bo-Xuan, Yao, Ming-Dong, Wang, Ying, Xiao, Wen-Hai, Yuan, Ying-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090239/
https://www.ncbi.nlm.nih.gov/pubmed/32258005
http://dx.doi.org/10.3389/fbioe.2020.00152