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Synemin Redefined: Multiple Binding Partners Results in Multifunctionality
Historically synemin has been studied as an intermediate filament protein. However, synemin also binds the type II regulatory (R) subunit α of protein kinase A (PKA) and protein phosphatase type 2A, thus participating in the PKA and phosphoinositide 3-kinase (PI3K)-Akt and signaling pathways. In add...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090255/ https://www.ncbi.nlm.nih.gov/pubmed/32258037 http://dx.doi.org/10.3389/fcell.2020.00159 |