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p62/Sequestosome 1 levels increase and phosphorylation is altered in Cx50D47A lenses, but deletion of p62/sequestosome 1 does not improve transparency
PURPOSE: p62/Sequestosome 1 (p62) is a stress-induced protein that is involved in several different intracellular pathways, including regulation of aspects of protein degradation. p62 levels are elevated in several types of cataracts. We investigated whether levels of p62 and its phosphorylation wer...
Autores principales: | Jara, Oscar, Mysliwiec, Hubert, Minogue, Peter J., Berthoud, Viviana M., Beyer, Eric C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090271/ https://www.ncbi.nlm.nih.gov/pubmed/32214786 |
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