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iStable 2.0: Predicting protein thermal stability changes by integrating various characteristic modules
Protein mutations can lead to structural changes that affect protein function and result in disease occurrence. In protein engineering, drug design or and optimization industries, mutations are often used to improve protein stability or to change protein properties while maintaining stability. To pr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090336/ https://www.ncbi.nlm.nih.gov/pubmed/32226595 http://dx.doi.org/10.1016/j.csbj.2020.02.021 |