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iStable 2.0: Predicting protein thermal stability changes by integrating various characteristic modules

Protein mutations can lead to structural changes that affect protein function and result in disease occurrence. In protein engineering, drug design or and optimization industries, mutations are often used to improve protein stability or to change protein properties while maintaining stability. To pr...

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Detalles Bibliográficos
Autores principales: Chen, Chi-Wei, Lin, Meng-Han, Liao, Chi-Chou, Chang, Hsung-Pin, Chu, Yen-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090336/
https://www.ncbi.nlm.nih.gov/pubmed/32226595
http://dx.doi.org/10.1016/j.csbj.2020.02.021