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Exploring 3D chromatin contacts in gene regulation: The evolution of approaches for the identification of functional enhancer-promoter interaction

Mechanisms underlying gene regulation are key to understand how multicellular organisms with various cell types develop from the same genetic blueprint. Dynamic interactions between enhancers and genes are revealed to play central roles in controlling gene transcription, but the determinants to link...

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Detalles Bibliográficos
Autores principales: Xu, Hang, Zhang, Shijie, Yi, Xianfu, Plewczynski, Dariusz, Li, Mulin Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090358/
https://www.ncbi.nlm.nih.gov/pubmed/32226593
http://dx.doi.org/10.1016/j.csbj.2020.02.013