Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin

The papain-like protease (PL(pro)) of Middle-East respiratory syndrome coronavirus (MERS-CoV) has proteolytic, deubiquitinating, and deISGylating activities. The latter two are involved in the suppression of the antiviral innate immune response of the host cell. To contribute to an understanding of...

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Detalles Bibliográficos
Autores principales: Lei, Jian, Hilgenfeld, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090527/
https://www.ncbi.nlm.nih.gov/pubmed/27245450
http://dx.doi.org/10.1007/s12250-016-3742-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090527/
https://www.ncbi.nlm.nih.gov/pubmed/27245450
http://dx.doi.org/10.1007/s12250-016-3742-4

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