Identification of effective siRNA blocking the expression of SARS viral envelope E and RDRP genes

A cell-based assay was developed to screen small interference RNA (siRNA) to block the expression of two genes of the severe acute respiratory syndrome (SARS) virus. These two genes encode RNA-dependent RNA polymerase (RDRP) and envelope E protein. The RDRP plays an essential role in viral RNA repli...

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Detalles Bibliográficos
Autores principales: Meng, Bo, Lui, Yue-woon, Meng, Shi, Cao, Changxiu, Hu, Yinghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Humana Press 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090727/
https://www.ncbi.nlm.nih.gov/pubmed/16757801
http://dx.doi.org/10.1385/MB:33:2:141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090727/
https://www.ncbi.nlm.nih.gov/pubmed/16757801
http://dx.doi.org/10.1385/MB:33:2:141

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