Identification of Phytochemicals Targeting c-Met Kinase Domain using Consensus Docking and Molecular Dynamics Simulation Studies

c-Met receptor tyrosine kinase is a proto-oncogene whose aberrant activation is attributed to a lower rate of survival in most cancers. Natural product-derived inhibitors known as “fourth generation inhibitors” constitute more than 60% of anticancer drugs. Furthermore, consensus docking approach has...

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Detalles Bibliográficos
Autores principales: Aliebrahimi, Shima, Montasser Kouhsari, Shideh, Ostad, Seyed Nasser, Arab, Seyed Shahriar, Karami, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090793/
https://www.ncbi.nlm.nih.gov/pubmed/28852971
http://dx.doi.org/10.1007/s12013-017-0821-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090793/
https://www.ncbi.nlm.nih.gov/pubmed/28852971
http://dx.doi.org/10.1007/s12013-017-0821-6

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