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Interaction of L-SIGN with Hepatitis C Virus Envelope Protein E2 Up-Regulates Raf–MEK–ERK Pathway

Liver/lymph node-specific intercellular adhesion molecule-3-grabbing integrin (L-SIGN) facilitates hepatitis C virus (HCV) infection through interaction with HCV envelope protein E2. Signaling events triggered by the E2 via L-SIGN are poorly understood. Here, kinase cascades of Raf–MEK–ERK pathway w...

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Detalles Bibliográficos
Autores principales: Zhao, Lan-Juan, Wang, Wen, Ren, Hao, Qi, Zhong-Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090805/
https://www.ncbi.nlm.nih.gov/pubmed/23292357
http://dx.doi.org/10.1007/s12013-012-9505-4