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The cytoskeletal motor proteins Dynein and MyoV direct apical transport of Crumbs

Crumbs (Crb in Drosophila; CRB1-3 in mammals) is a transmembrane determinant of epithelial cell polarity and a regulator of Hippo signalling. Crb is normally localized to apical cell-cell contacts, just above adherens junctions, but how apical trafficking of Crb is regulated in epithelial cells rema...

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Detalles Bibliográficos
Autores principales: Aguilar-Aragon, M., Fletcher, G., Thompson, B.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090908/
https://www.ncbi.nlm.nih.gov/pubmed/31881198
http://dx.doi.org/10.1016/j.ydbio.2019.12.009