Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV)

Aryl diketoacid (ADK) is well known for antiviral activity which can be enhanced by introduction of an aromatic arylmethyl substituent. A natural flavonoid quercetin has a 3,5-dihydroxychromone pharmacophore which is in bioisosteric relationship with the 1,3-diketoacid moiety of the ADK. Thus, it wa...

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Detalles Bibliográficos
Autores principales: Park, Hye Ri, Yoon, Hyunjun, Kim, Mi Kyoung, Lee, Sung Dae, Chong, Youhoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pharmaceutical Society of Korea 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090976/
https://www.ncbi.nlm.nih.gov/pubmed/22297745
http://dx.doi.org/10.1007/s12272-012-0108-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090976/
https://www.ncbi.nlm.nih.gov/pubmed/22297745
http://dx.doi.org/10.1007/s12272-012-0108-9

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