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Different Vinculin Binding Sites Use the Same Mechanism to Regulate Directional Force Transduction

Vinculin is a universal adaptor protein that transiently reinforces the mechanical stability of adhesion complexes. It stabilizes mechanical connections that cells establish between the actomyosin cytoskeleton and the extracellular matrix via integrins or to neighboring cells via cadherins, yet litt...

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Detalles Bibliográficos
Autores principales: Kluger, Carleen, Braun, Lukas, Sedlak, Steffen M., Pippig, Diana A., Bauer, Magnus S., Miller, Ken, Milles, Lukas F., Gaub, Hermann E., Vogel, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091509/
https://www.ncbi.nlm.nih.gov/pubmed/32109366
http://dx.doi.org/10.1016/j.bpj.2019.12.042