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Different Vinculin Binding Sites Use the Same Mechanism to Regulate Directional Force Transduction
Vinculin is a universal adaptor protein that transiently reinforces the mechanical stability of adhesion complexes. It stabilizes mechanical connections that cells establish between the actomyosin cytoskeleton and the extracellular matrix via integrins or to neighboring cells via cadherins, yet litt...
Autores principales: | Kluger, Carleen, Braun, Lukas, Sedlak, Steffen M., Pippig, Diana A., Bauer, Magnus S., Miller, Ken, Milles, Lukas F., Gaub, Hermann E., Vogel, Viola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091509/ https://www.ncbi.nlm.nih.gov/pubmed/32109366 http://dx.doi.org/10.1016/j.bpj.2019.12.042 |
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