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Synthesis of Novel Heterocycles by Amide Activation and Umpolung Cyclization
[Image: see text] Herein, we report a metal-free synthesis of cyclic amidines, oxazines, and an oxazinone under mild conditions by electrophilic amide activation. This strategy features an unusual Umpolung cyclization mode and enables the smooth union of α-aryl amides and diverse alkylazides, effect...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091535/ https://www.ncbi.nlm.nih.gov/pubmed/32159354 http://dx.doi.org/10.1021/acs.orglett.0c00571 |