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The Effects of Mechanical Preload on Transmural Differences in Mechano-Calcium-Electric Feedback in Single Cardiomyocytes: Experiments and Mathematical Models

Transmural differences in ventricular myocardium are maintained by electromechanical coupling and mechano-calcium/mechano-electric feedback. In the present study, we experimentally investigated the influence of preload on the force characteristics of subendocardial (Endo) and subepicardial (Epi) sin...

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Detalles Bibliográficos
Autores principales: Khokhlova, Anastasia, Konovalov, Pavel, Iribe, Gentaro, Solovyova, Olga, Katsnelson, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091561/
https://www.ncbi.nlm.nih.gov/pubmed/32256377
http://dx.doi.org/10.3389/fphys.2020.00171