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The Effects of Mechanical Preload on Transmural Differences in Mechano-Calcium-Electric Feedback in Single Cardiomyocytes: Experiments and Mathematical Models
Transmural differences in ventricular myocardium are maintained by electromechanical coupling and mechano-calcium/mechano-electric feedback. In the present study, we experimentally investigated the influence of preload on the force characteristics of subendocardial (Endo) and subepicardial (Epi) sin...
Autores principales: | Khokhlova, Anastasia, Konovalov, Pavel, Iribe, Gentaro, Solovyova, Olga, Katsnelson, Leonid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091561/ https://www.ncbi.nlm.nih.gov/pubmed/32256377 http://dx.doi.org/10.3389/fphys.2020.00171 |
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