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siRNA targeting the Leader sequence of SARS-CoV inhibits virus replication

SARS-CoV (the SARS-Associated Coronavirus) was reported as a novel virus member in the coronavirus family, which was the cause of severe acute respiratory syndrome. Coronavirus replication occurs through a unique mechanism employing Leader sequence in the transcripts when initiating transcription fr...

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Detalles Bibliográficos
Autores principales: Li, T, Zhang, Y, Fu, L, Yu, C, Li, X, Li, Y, Zhang, X, Rong, Z, Wang, Y, Ning, H, Liang, R, Chen, W, Babiuk, L A, Chang, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091583/
https://www.ncbi.nlm.nih.gov/pubmed/15772689
http://dx.doi.org/10.1038/sj.gt.3302479