Human 8-oxoguanine DNA glycosylase increases resistance to hyperoxic cytotoxicity in lung epithelial cells and involvement with altered MAPK activity

It is unknown whether base excision DNA repair (BER) proteins interact with mitogen-activated protein kinases (MAPK) under oxidation. Here, we explored roles of BER proteins in signaling transduction involving MAPK during hyperoxia. We demonstrated that ERK1/2 phosphorylation in A549 cells was incre...

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Detalles Bibliográficos
Autores principales: Kannan, S, Pang, H, Foster, D C, Rao, Z, Wu, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091608/
https://www.ncbi.nlm.nih.gov/pubmed/16052235
http://dx.doi.org/10.1038/sj.cdd.4401736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091608/
https://www.ncbi.nlm.nih.gov/pubmed/16052235
http://dx.doi.org/10.1038/sj.cdd.4401736

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