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Many cuts to ruin: a comprehensive update of caspase substrates

Apoptotic cell death is executed by the caspase-mediated cleavage of various vital proteins. Elucidating the consequences of this endoproteolytic cleavage is crucial for our understanding of cell death and other biological processes. Many caspase substrates are just cleaved as bystanders, because th...

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Detalles Bibliográficos
Autores principales: Fischer, U, Jänicke, R U, Schulze-Osthoff, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091709/
https://www.ncbi.nlm.nih.gov/pubmed/12655297
http://dx.doi.org/10.1038/sj.cdd.4401160