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PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production

Infections by coronaviruses such as severe acute respiratory syndrome (SARS) coronavirus (SCoV) and mouse hepatitis virus A59 (MHV-A59) result in very little type I interferon (IFN) production by host cells, which is potentially responsible for the rapid viral growth and severe immunopathology assoc...

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Detalles Bibliográficos
Autores principales: Zheng, Dahai, Chen, Gang, Guo, Beichu, Cheng, Genhong, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091798/
https://www.ncbi.nlm.nih.gov/pubmed/18957937
http://dx.doi.org/10.1038/cr.2008.294