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PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production
Infections by coronaviruses such as severe acute respiratory syndrome (SARS) coronavirus (SCoV) and mouse hepatitis virus A59 (MHV-A59) result in very little type I interferon (IFN) production by host cells, which is potentially responsible for the rapid viral growth and severe immunopathology assoc...
Autores principales: | Zheng, Dahai, Chen, Gang, Guo, Beichu, Cheng, Genhong, Tang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091798/ https://www.ncbi.nlm.nih.gov/pubmed/18957937 http://dx.doi.org/10.1038/cr.2008.294 |
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