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Polycations increase the efficiency of adenovirus-mediated gene transfer to epithelial and endothelial cells in vitro
Recombinant adenoviruses are being developed for gene therapy for cystic fibrosis and other lung diseases, and for prevention and treatment of vascular thrombosis. A major limitation to the clinical utility of adenoviruses is the low efficiency of gene transfer achieved in vivo. In addition, little...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
1997
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091802/ https://www.ncbi.nlm.nih.gov/pubmed/9068793 http://dx.doi.org/10.1038/sj.gt.3300349 |