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Apical barriers to airway epithelial cell gene transfer with amphotropic retroviral vectors

Gene transfer to airway epithelia with amphotropic pseudotyped retroviral vectors is inefficient following apical vector application. To better understand this inefficiency, we localized the expression of Pit2, the amphotropic receptor, in polarized human airway epithelia. Pit2 was expressed on both...

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Detalles Bibliográficos
Autores principales: Wang, G, Williams, G, Xia, H, Hickey, M, Shao, J, Davidson, BL, McCray, PB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091907/
https://www.ncbi.nlm.nih.gov/pubmed/12085240
http://dx.doi.org/10.1038/sj.gt.3301714