Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies

The prevalence of adeno-associated virus (AAV) has been investigated in bat populations, but little is known about the biological properties of this virus. In this study, four full-length bat AAV capsid genes were isolated in China, with their amino acid sequences sharing 61% identity with those of...

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Detalles Bibliográficos
Autores principales: Li, Ya, Li, Jialu, Liu, Yunbo, Shi, Zhengli, Liu, Haizhou, Wei, Yuquan, Yang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091930/
https://www.ncbi.nlm.nih.gov/pubmed/31110296
http://dx.doi.org/10.1038/s41434-019-0081-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091930/
https://www.ncbi.nlm.nih.gov/pubmed/31110296
http://dx.doi.org/10.1038/s41434-019-0081-8

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