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Immunogenicity and Immune Silence in Human Cancer

Despite recent advances in cancer immunotherapy, the process of immunoediting early in tumorigenesis remains obscure. Here, we employ a mathematical model that utilizes the Cancer Genome Atlas (TCGA) data to elucidate the contribution of individual mutations and HLA alleles to the immunoediting proc...

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Detalles Bibliográficos
Autores principales: Yarmarkovich, Mark, Farrel, Alvin, Sison, Artemio, di Marco, Moreno, Raman, Pichai, Parris, Joshua L., Monos, Dimitrios, Lee, Hongzhe, Stevanovic, Stefan, Maris, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092187/
https://www.ncbi.nlm.nih.gov/pubmed/32256484
http://dx.doi.org/10.3389/fimmu.2020.00069