Botulinum toxin type A promotes microglial M2 polarization and suppresses chronic constriction injury-induced neuropathic pain through the P2X7 receptor

BACKGROUND: Switching microglial polarization from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype represents a novel therapeutic strategy for neuropathic pain (NP). This study aims to investigate whether botulinum toxin type A (BTX-A) regulates microglial M1/M2 polarization...

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Detalles Bibliográficos
Autores principales: Gui, Xianwei, Wang, Hansen, Wu, Lanxiang, Tian, Sheng, Wang, Xuan, Zheng, Heqing, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092425/
https://www.ncbi.nlm.nih.gov/pubmed/32211150
http://dx.doi.org/10.1186/s13578-020-00405-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092425/
https://www.ncbi.nlm.nih.gov/pubmed/32211150
http://dx.doi.org/10.1186/s13578-020-00405-3

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