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Urolithin a attenuates IL-1β-induced inflammatory responses and cartilage degradation via inhibiting the MAPK/NF-κB signaling pathways in rat articular chondrocytes

BACKGROUND: Osteoarthritis (OA) is characterized by inflammation and extracellular matrix (ECM) degradation and is one of the most common chronic degenerative joint diseases that causes pain and disability in adults. Urolithin A (UA) has been widely reported for its anti-inflammatory properties in s...

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Detalles Bibliográficos
Autores principales: Ding, Sheng-long, Pang, Zhi-ying, Chen, Xue-mei, Li, Zheng, Liu, Xin-xin, Zhai, Qi-lin, Huang, Jun-ming, Ruan, Zhi-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092521/
https://www.ncbi.nlm.nih.gov/pubmed/32210738
http://dx.doi.org/10.1186/s12950-020-00242-8