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Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells

BACKGROUND: Mast cells (MCs) have been found to play a critical role during development of inflammatory bowel disease (IBD) that characterized by dysregulation of inflammation and impaired intestinal barrier function. However, the function of MCs in IBD remains to be fully elucidated. RESULTS: In ou...

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Detalles Bibliográficos
Autores principales: Li, Musheng, Zhao, Junhong, Cao, Meiwan, Liu, Ruitao, Chen, Guanhua, Li, Songyu, Xie, Yuanwen, Xie, Jing, Cheng, Yang, Huang, Ling, Su, Mingmin, Xu, Yuxin, Zheng, Mingyue, Zou, Kejian, Geng, Lanlan, Xu, Wanfu, Gong, Sitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092522/
https://www.ncbi.nlm.nih.gov/pubmed/32209121
http://dx.doi.org/10.1186/s40659-020-00279-2