RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors

BACKGROUND: Invasive urothelial carcinoma (iUC) is highly similar between dogs and humans in terms of pathologic presentation, molecular subtypes, response to treatment and age at onset. Thus, the dog is an established and relevant model for testing and development of targeted drugs benefiting both...

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Detalles Bibliográficos
Autores principales: Parker, Heidi G., Dhawan, Deepika, Harris, Alex C., Ramos-Vara, Jose A., Davis, Brian W., Knapp, Deborah W., Ostrander, Elaine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092566/
https://www.ncbi.nlm.nih.gov/pubmed/32209086
http://dx.doi.org/10.1186/s12885-020-06737-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092566/
https://www.ncbi.nlm.nih.gov/pubmed/32209086
http://dx.doi.org/10.1186/s12885-020-06737-0

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