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High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells
BACKGROUND: DNA replication in mammalian cells occurs in a defined temporal order during S phase, known as the replication timing (RT) programme. Replication timing is developmentally regulated and correlated with chromatin conformation and local transcriptional potential. Here, we present RT profil...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092589/ https://www.ncbi.nlm.nih.gov/pubmed/32209126 http://dx.doi.org/10.1186/s13059-020-01983-8 |