High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells

BACKGROUND: DNA replication in mammalian cells occurs in a defined temporal order during S phase, known as the replication timing (RT) programme. Replication timing is developmentally regulated and correlated with chromatin conformation and local transcriptional potential. Here, we present RT profil...

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Detalles Bibliográficos
Autores principales: Zhao, Peiyao A., Sasaki, Takayo, Gilbert, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092589/
https://www.ncbi.nlm.nih.gov/pubmed/32209126
http://dx.doi.org/10.1186/s13059-020-01983-8

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