Oligomannuronate prevents mitochondrial dysfunction induced by IAPP in RINm5F islet cells by inhibition of JNK activation and cell apoptosis

BACKGROUND: Oligomannuronates (OM) are natural products from alginate that is frequently used as food supplement. The aim of this study was to investigate the in vitro protective effects of OM on RINm5F cells against human Islet amyloid polypeptide (IAPP) induced mitochondrial dysfunction, as well a...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Li, Qiong, Cheng, Xiaolei, Liu, Zhichun, Zhao, Xiaoliang, Zhang, Shuai, Yu, Guangli, Zhao, Xia, Hao, Jiejie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092590/
https://www.ncbi.nlm.nih.gov/pubmed/32226477
http://dx.doi.org/10.1186/s13020-020-00310-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092590/
https://www.ncbi.nlm.nih.gov/pubmed/32226477
http://dx.doi.org/10.1186/s13020-020-00310-4

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