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Exosomal MALAT1 sponges miR-26a/26b to promote the invasion and metastasis of colorectal cancer via FUT4 enhanced fucosylation and PI3K/Akt pathway

BACKGROUND: Exosomes are vesicles of endocytic origin released by various cell types and emerging as important mediators in tumor cells. Human metastases-associated lung adenocarcinoma transcript 1 (MALAT1) is a long non-coding RNA known to promote cell proliferation, metastasis, and invasion in col...

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Detalles Bibliográficos
Autores principales: Xu, Jingchao, Xiao, Yang, Liu, Bing, Pan, Shimeng, Liu, Qianqian, Shan, Yujia, Li, Shuangda, Qi, Yu, Huang, Yiran, Jia, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092616/
https://www.ncbi.nlm.nih.gov/pubmed/32209115
http://dx.doi.org/10.1186/s13046-020-01562-6