Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R

Understanding the functional consequence of rare cystic fibrosis (CF) mutations is mandatory for the adoption of precision therapeutic approaches for CF. Here we studied the effect of the very rare CF mutation, W361R, on CFTR processing and function. We applied western blot, patch clamp and pharmaco...

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Detalles Bibliográficos
Autores principales: Billet, Arnaud, Elbahnsi, Ahmad, Jollivet-Souchet, Mathilde, Hoffmann, Brice, Mornon, Jean-Paul, Callebaut, Isabelle, Becq, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092619/
https://www.ncbi.nlm.nih.gov/pubmed/32256364
http://dx.doi.org/10.3389/fphar.2020.00295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092619/
https://www.ncbi.nlm.nih.gov/pubmed/32256364
http://dx.doi.org/10.3389/fphar.2020.00295

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