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Exonuclease 1 (Exo1) Participates in Mammalian Non-Homologous End Joining and Contributes to Drug Resistance in Ovarian Cancer

BACKGROUND: Exonuclease 1 (Exo1) participates in a variety of DNA damage repair, including mismatch repair, nucleotide excision repair, and homologous recombination. Genetic study in yeast indicates a role of Exo1 in non-homologous end joining (NHEJ), acting as a regulator for accuracy repairing DNA...

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Detalles Bibliográficos
Autores principales: He, Dongyun, Li, Tao, Sheng, Minjia, Yang, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092659/
https://www.ncbi.nlm.nih.gov/pubmed/32167078
http://dx.doi.org/10.12659/MSM.918751