Local effect of simvastatin combined with different osteoconductive biomaterials and collagen sponge on new bone formation in critical defects in rat calvaria

PURPOSE: To evaluate the local effect of simvastatin (SVT) combined with deproteinized bovine bone (DBB) with hydroxyapatite/β-tricalcium phosphate biphasic ceramics (HA/TCP) and with collagen sponge (CS) on bone repair in critical size defects (CSDs) in rat calvaria. METHODS: Forty-two 5-mm diamete...

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Detalles Bibliográficos
Autores principales: de Sousa, Dircilei Nascimento, Roriz, Virgílio Moreira, de Oliveira, Guilherme José Pimentel Lopes, Duarte, Wagner Rodrigues, Pinto, Leonardo Nogueira de Miranda Pereira, Vianna, Leonora Maciel de Souza, Carneiro, Fabiana Pirani, Ferreira, Vania Maria Moraes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092666/
https://www.ncbi.nlm.nih.gov/pubmed/32215463
http://dx.doi.org/10.1590/s0102-865020200010000002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092666/
https://www.ncbi.nlm.nih.gov/pubmed/32215463
http://dx.doi.org/10.1590/s0102-865020200010000002

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