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Local effect of simvastatin combined with different osteoconductive biomaterials and collagen sponge on new bone formation in critical defects in rat calvaria
PURPOSE: To evaluate the local effect of simvastatin (SVT) combined with deproteinized bovine bone (DBB) with hydroxyapatite/β-tricalcium phosphate biphasic ceramics (HA/TCP) and with collagen sponge (CS) on bone repair in critical size defects (CSDs) in rat calvaria. METHODS: Forty-two 5-mm diamete...
Autores principales: | de Sousa, Dircilei Nascimento, Roriz, Virgílio Moreira, de Oliveira, Guilherme José Pimentel Lopes, Duarte, Wagner Rodrigues, Pinto, Leonardo Nogueira de Miranda Pereira, Vianna, Leonora Maciel de Souza, Carneiro, Fabiana Pirani, Ferreira, Vania Maria Moraes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092666/ https://www.ncbi.nlm.nih.gov/pubmed/32215463 http://dx.doi.org/10.1590/s0102-865020200010000002 |
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